XIRP1

Across TCGA cell cohorts, XIRP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 875 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible XIRP1-associated GO terms across cancer lineages are Cellular response to chemical stress, Protein lipidation, and Negative regulation of post-translational protein modification. Each is linked with XIRP1 in more than 5 cancer types. Because this analysis shows association rather than direction, both XIRP1-to-partner and partner-to-XIRP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cellular response to chemical stress grouped by XIRP1-low versus XIRP1-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (XIRP1→partner) and Y-score (partner→XIRP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Cellular response to chemical stress →	+0.044	+0.135	<.001	.002	3	6
LUNG_SCLC	Protein lipidation →	+0.058	+0.047	.003	.005	3	5
BLOOD_Lymphoma	Negative regulation of post-translational protein modification →	+0.069	+0.106	<.001	.001	3	4
LUNG_NSCLC_LUAD	Leukemia inhibitory factor signaling pathway →	+0.130	+0.012	<.001	<.001	3	4
LARGE_INTESTINE	Positive regulation of oxidoreductase activity →	-0.119	-0.016	.001	<.001	3	4
SOFT_TISSUE	Regulation of type III interferon production →	+0.829	+0.680	.001	.003	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 875 associations by consensus.

Cellular response to chemical stress by XIRP1 expression — BLOOD_Lymphoma

Explore this box plot interactively →