XIAPP2

Across TCGA patient cohorts, XIAPP2 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,739 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible XIAPP2-associated proteins across cancer lineages are RSF1, YTHDC1, and RPL26. Each is linked with XIAPP2 in more than 4 cancer types. Because this analysis shows association rather than direction, both XIAPP2-to-partner and partner-to-XIAPP2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, XIAPP2 versus RSF1 in LSCC, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (XIAPP2→partner) and Y-score (partner→XIAPP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	RSF1 →	+0.393	+0.341	<.001	<.001	3	5
LSCC	YTHDC1 →	+0.265	+0.346	<.001	.001	3	4
GBM	RPL26 →	-0.839	-0.474	<.001	.002	3	4
GBM	RPS6 →	-0.463	-0.313	.004	.001	3	4
LSCC	RSF1_S604 →	+0.309	+0.290	<.001	<.001	3	4
LSCC	HNRNPLL →	+0.207	+0.363	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,739 associations by consensus.

XIAPP2 vs RSF1 — LSCC

Explore this scatter interactively →