XIAP-AS1

Across TCGA patient cohorts, XIAP-AS1 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,433 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible XIAP-AS1-associated proteins across cancer lineages are RBM14_T206, SEC63_T537, and MAP1B_S992. Each is linked with XIAP-AS1 in more than 3 cancer types. Because this analysis shows association rather than direction, both XIAP-AS1-to-partner and partner-to-XIAP-AS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, XIAP-AS1 versus RBM14_T206 in PDAC, with a Pearson correlation of 0.33.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (XIAP-AS1→partner) and Y-score (partner→XIAP-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	RBM14_T206 →	+0.627	+0.374	<.001	.003	3	4
CCRCC	SEC63_T537 →	-0.802	-0.452	<.001	.001	3	4
LSCC	MAP1B_S992 →	+1.030	+0.776	<.001	<.001	3	4
PDAC	PHF3_S1184 →	+0.692	+0.560	.002	<.001	3	3
PDAC	ARHGEF11_S35 →	+0.469	+0.343	<.001	<.001	3	3
BRCA	TCEAL3_S65 →	+0.651	+0.235	.003	.006	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,433 associations by consensus.

XIAP-AS1 vs RBM14_T206 — PDAC

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