XCL2

Across TCGA patient cohorts, XCL2 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,650 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible XCL2-associated proteins across cancer lineages are SEPTIN1, IL16, and ISG20. Each is linked with XCL2 in more than 7 cancer types. Because this analysis shows association rather than direction, both XCL2-to-partner and partner-to-XCL2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, XCL2 versus SEPTIN1 in BRCA, with a Pearson correlation of 0.78.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (XCL2→partner) and Y-score (partner→XCL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SEPTIN1 →	+0.889	+1.397	<.001	<.001	3	8
BRCA	IL16 →	+0.627	+1.409	<.001	<.001	3	7
BRCA	ISG20 →	+0.753	+1.375	<.001	<.001	3	7
OV	LCP1 →	+0.690	+1.134	<.001	<.001	3	7
BRCA	APOL3 →	+0.788	+1.401	<.001	<.001	3	7
OV	ADA2 →	+0.599	+1.459	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,650 associations by consensus.

XCL2 vs SEPTIN1 — BRCA

Explore this scatter interactively →