XAGE5

Across TCGA patient cohorts, XAGE5 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,279 significant associations in total. STAD shows the largest number of these associations.

The most reproducible XAGE5-associated GO terms across cancer lineages are Protein localization to chromosome, Mitochondrial DNA metabolic process, and Mitochondrial translation. Each is linked with XAGE5 in more than 8 cancer types. Because this analysis shows association rather than direction, both XAGE5-to-partner and partner-to-XAGE5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein localization to chromosome grouped by XAGE5-low versus XAGE5-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (XAGE5→partner) and Y-score (partner→XAGE5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Protein localization to chromosome →	+0.061	+0.205	<.001	<.001	3	9
STAD	Mitochondrial DNA metabolic process →	+0.063	+0.356	<.001	<.001	3	9
STAD	Mitochondrial translation →	+0.076	+0.232	<.001	<.001	3	9
STAD	Mitochondrial respiratory chain complex assembly →	+0.071	+0.218	<.001	<.001	3	9
STAD	Amino acid activation →	+0.058	+0.224	<.001	<.001	3	9
STAD	Regulation of DNA replication →	+0.064	+0.285	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,279 associations by consensus.

Protein localization to chromosome by XAGE5 expression — STAD

Explore this box plot interactively →