XAGE5

Across TCGA pan-cancer cohorts, XAGE5 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of XAGE5’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where XAGE5 RNA is repressed in tumor relative to normal tissue. In most cancer types XAGE5 is over-expressed in tumor, although a few such as BRCA show the opposite, repressed pattern.

BRCA and LIHC are the cancer types where XAGE5 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in XAGE5 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	Female	All	−0.054	.018	6	view →
LIHC	All	All	+0.724	.001	3	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

XAGE5–BRCA

Open the BRCA breakdown →