Across TCGA pan-cancer cohorts, XAGE1B RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of XAGE1B’s most consistent transcriptional readouts.
The strongest signal is observed in lung adenocarcinoma (LUAD), where XAGE1B RNA is more highly expressed in tumor relative to normal tissue. In most cancer types XAGE1B is over-expressed in tumor.
LUAD and LIHC are the cancer types where XAGE1B tumor–normal differential expression is most reproducible.