XAB2

Across TCGA patient cohorts, XAB2 protein abundance is significantly associated with the RNA expression of many other genes, with 16,737 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible XAB2-associated genes across cancer lineages are E2F1, CDCA8, and DTL. Each is linked with XAB2 in more than 7 cancer types. Because this analysis shows association rather than direction, both XAB2-to-partner and partner-to-XAB2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, XAB2 versus E2F1 in UCEC, with a Pearson correlation of 0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (XAB2→partner) and Y-score (partner→XAB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	E2F1 →	+1.122	+0.169	.001	.002	3	8
LUAD	CDCA8 →	+1.055	+0.183	<.001	<.001	3	8
GBM	DTL →	+0.987	+0.202	<.001	<.001	3	8
LSCC	NCAPG2 →	+0.810	+0.282	<.001	<.001	3	8
HNSC	SSRP1 →	+0.662	+0.158	<.001	<.001	3	8
GBM	DSN1 →	+0.610	+0.198	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,737 associations by consensus.

XAB2 vs E2F1 — UCEC

Explore this scatter interactively →