Across TCGA patient cohorts, WWP2 protein abundance is significantly associated with the RNA expression of many other genes, with 12,363 significant associations in total. GBM shows the largest number of these associations.

The most reproducible WWP2-associated genes across cancer lineages are CNOT1, DUS2, and HSBP1. Each is linked with WWP2 in more than 6 cancer types. Because this analysis shows association rather than direction, both WWP2-to-partner and partner-to-WWP2 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WWP2→partner) and Y-score (partner→WWP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CNOT1 →	+0.456	+0.244	<.001	.008	3	7
HNSC	DUS2 →	+0.524	+0.272	<.001	<.001	3	7
UCEC	HSBP1 →	+0.647	+0.267	.001	.001	3	7
HNSC	CIAPIN1 →	+0.767	+0.318	<.001	<.001	3	7
BRCA	AARS1 →	+0.571	+0.350	<.001	<.001	3	7
UCEC	PSMD7 →	+0.662	+0.297	.001	<.001	2	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,363 associations by consensus.

Exploration

WWP2 survival (RNA) · tumor vs normal (RNA) · all WWP2 data types