Across TCGA cell cohorts, WWOX RNA expression is significantly associated with the go_rna of many other GO terms, with 4,991 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible WWOX-associated GO terms across cancer lineages are Nucleic acid transport, RNA transport, and mRNA alternative polyadenylation. Each is linked with WWOX in more than 14 cancer types. Because this analysis shows association rather than direction, both WWOX-to-partner and partner-to-WWOX results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (WWOX→partner) and Y-score (partner→WWOX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Nucleic acid transport →	+0.093	+1.218	<.001	.002	3	15
BONE	RNA transport →	+0.093	+1.218	<.001	.002	3	15
BONE	mRNA alternative polyadenylation →	+0.109	+1.765	.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Cell cycle DNA replication initiation →	+0.200	+1.390	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Nuclear cell cycle DNA replication initiation →	+0.200	+1.390	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Mitotic DNA replication initiation →	+0.200	+1.390	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,991 associations by consensus.

Exploration

WWOX survival (RNA) · tumor vs normal (RNA) · all WWOX data types