WWOX-AS1

Across TCGA patient cohorts, WWOX-AS1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,370 significant associations in total. STAD shows the largest number of these associations.

The most reproducible WWOX-AS1-associated GO terms across cancer lineages are Membrane docking, Transport along microtubule, and Respiratory chain complex IV assembly. Each is linked with WWOX-AS1 in more than 11 cancer types. Because this analysis shows association rather than direction, both WWOX-AS1-to-partner and partner-to-WWOX-AS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Membrane docking grouped by WWOX-AS1-low versus WWOX-AS1-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (WWOX-AS1→partner) and Y-score (partner→WWOX-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Membrane docking →	+0.061	+0.409	.002	<.001	3	12
ESCA	Transport along microtubule →	+0.059	+0.369	.001	<.001	3	12
ESCA	Respiratory chain complex IV assembly →	+0.065	+0.436	<.001	<.001	3	12
ESCA	Microtubule-based transport →	+0.045	+0.337	.002	<.001	3	11
ESCA	Facultative heterochromatin formation →	+0.057	+0.332	.003	<.001	3	11
ESCA	Regulation of telomere maintenance via telomere lengthening →	+0.072	+0.470	.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,370 associations by consensus.

Membrane docking by WWOX-AS1 expression — ESCA

Explore this box plot interactively →