WWC2-AS2

Across TCGA pan-cancer cohorts, WWC2-AS2 RNA is linked to patient survival in 27 of 34 cancer types, making it the most broadly survival-associated WWC2-AS2 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher WWC2-AS2 RNA is associated with better overall survival. In most high-consensus cancer types, elevated WWC2-AS2 expression acts as an unfavorable survival marker, although some lineages such as KIRC and KIRP show a favorable association.

KIRC, LUAD, and KIRP are the cancer types where WWC2-AS2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Median	All	0.713	0.549	<.001	126	view →
LUAD	DFS	Median	All	0.594	0.735	<.001	78	view →
KIRP	DFS	Median	All	0.925	0.537	<.001	67	view →
HNSC	OS	Quartile	III,IV	0.281	0.521	.001	54	view →
ESCA	OS	Tertile	II,III,IV	0.649	0.343	.001	43	view →
UCS	DFS	Tertile	II,III,IV	0.658	0.136	.001	42	view →
LGG	DFS	Median	All	0.669	0.797	<.001	42	view →
CESC	DFS	Median	All	0.651	0.818	<.001	40	view →
UVM	DFS	Quartile	All	0.801	0.388	.003	32	view →
MESO	OS	Quartile	II,III,IV	0.571	0.242	.002	26	view →
LAML	DFS	Quartile	All	0.828	0.433	.005	24	view →
STAD	OS	Median	II,III,IV	0.288	0.531	.001	22	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 27 lineages.

WWC2-AS2–KIRC (OS)

Open the KIRC breakdown →