WWC2-AS1

Across TCGA patient cohorts, WWC2-AS1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,607 significant associations in total. STAD shows the largest number of these associations.

The most reproducible WWC2-AS1-associated GO terms across cancer lineages are Hippo signaling, Regulation of actin filament bundle assembly, and Substrate adhesion-dependent cell spreading. Each is linked with WWC2-AS1 in more than 13 cancer types. Because this analysis shows association rather than direction, both WWC2-AS1-to-partner and partner-to-WWC2-AS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Hippo signaling grouped by WWC2-AS1-low versus WWC2-AS1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (WWC2-AS1→partner) and Y-score (partner→WWC2-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Hippo signaling →	+0.056	+0.244	<.001	<.001	3	14
ESCA	Regulation of actin filament bundle assembly →	+0.053	+0.279	<.001	<.001	3	13
STAD	Substrate adhesion-dependent cell spreading →	+0.061	+0.229	<.001	<.001	3	13
ESCA	Regulation of non-canonical NF-kappaB signal transduction →	+0.066	+0.333	<.001	<.001	3	13
STAD	Negative regulation of cytoskeleton organization →	+0.049	+0.214	<.001	<.001	3	13
STAD	Positive regulation of cytoskeleton organization →	+0.056	+0.226	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,607 associations by consensus.

Hippo signaling by WWC2-AS1 expression — STAD

Explore this box plot interactively →