WWC2-AS1

Across TCGA pan-cancer cohorts, WWC2-AS1 RNA is linked to patient survival in 16 of 34 cancer types, making it the most broadly survival-associated WWC2-AS1 data layer.

The strongest signal is observed in rectum adenocarcinoma (READ), where higher WWC2-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated WWC2-AS1 expression acts as an unfavorable survival marker, although some lineages such as ESCA and UCS show a favorable association.

READ, CESC, and ESCA are the cancer types where WWC2-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
READ	DFS	Tertile	All	0.234	0.597	.017	42	view →
CESC	OS	Tertile	IV	0.121	0.591	.029	36	view →
ESCA	OS	Tertile	III,IV	0.693	0.311	.004	34	view →
SKCM	DFS	Tertile	All	0.443	0.659	.006	27	view →
ACC	OS	Tertile	II,III,IV	0.565	0.877	.004	27	view →
UCS	DFS	Tertile	IV	0.996	0.570	.039	24	view →
LUAD	DFS	Quartile	II,III,IV	0.377	0.615	.007	23	view →
BLCA	DFS	Tertile	IV	0.256	0.387	.019	21	view →
GBM	OS	Tertile	All	0.084	0.421	<.001	18	view →
COAD	OS	Tertile	IV	0.089	0.658	.012	18	view →
KIRP	OS	Tertile	II,III,IV	0.203	0.645	.019	18	view →
LAML	DFS	Quartile	All	0.561	0.292	.014	16	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 16 lineages.

WWC2-AS1–READ (DFS)

Open the READ breakdown →