WWC1

Across TCGA patient cohorts, WWC1 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,639 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible WWC1-associated proteins across cancer lineages are WWC1_S535, WWC1_S899, and LRBA. Each is linked with WWC1 in more than 6 cancer types. Because this analysis shows association rather than direction, both WWC1-to-partner and partner-to-WWC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, WWC1 versus WWC1_S535 in LSCC, with a Pearson correlation of 0.52.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (WWC1→partner) and Y-score (partner→WWC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	WWC1_S535 →	+0.732	+0.744	<.001	<.001	3	7
OV	WWC1_S899 →	+0.674	+0.849	.001	.003	3	6
HNSC	LRBA →	+0.259	+0.451	<.001	.001	3	5
UCEC	CLINT1 →	+0.260	+0.509	.002	.002	3	5
UCEC	WWC1_S947 →	+0.644	+0.834	<.001	<.001	3	5
HNSC	OCLN →	+0.723	+0.495	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,639 associations by consensus.

WWC1 vs WWC1_S535 — LSCC

Explore this scatter interactively →