WWC1

Across TCGA patient cohorts, WWC1 protein abundance is significantly associated with the RNA expression of many other genes, with 8,792 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible WWC1-associated genes across cancer lineages are SIDT1, NPM3, and TMEM125. Each is linked with WWC1 in more than 3 cancer types. Because this analysis shows association rather than direction, both WWC1-to-partner and partner-to-WWC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, WWC1 versus SIDT1 in BRCA, with a Pearson correlation of 0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WWC1→partner) and Y-score (partner→WWC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SIDT1 →	+1.290	+0.348	.001	<.001	3	4
BRCA	NPM3 →	-0.829	-0.348	.001	<.001	3	4
LSCC	TMEM125 →	+1.053	+0.408	<.001	<.001	3	4
UCEC	ESRP2 →	+0.630	+0.418	<.001	<.001	3	3
UCEC	HSD17B4 →	+0.496	+0.376	.007	.004	3	3
UCEC	ALPL →	+1.376	+0.353	.004	.007	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,792 associations by consensus.

WWC1 vs SIDT1 — BRCA

Explore this scatter interactively →