WWC1

Across TCGA cell cohorts, WWC1 RNA expression is significantly associated with the RNA expression of many other genes, with 7,731 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible WWC1-associated genes across cancer lineages are TUFT1, STX3, and KRT8. Each is linked with WWC1 in more than 9 cancer types. Because this analysis shows association rather than direction, both WWC1-to-partner and partner-to-WWC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, WWC1 versus TUFT1 in BONE, with a Pearson correlation of 0.59.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WWC1→partner) and Y-score (partner→WWC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	TUFT1 →	+2.683	+2.013	<.001	.001	3	9
STOMACH	STX3 →	+1.653	+1.712	<.001	<.001	3	9
BONE	KRT8 →	+2.620	+1.797	.005	.001	2	10
LUNG_NSCLC_LUSC	EZR →	+1.850	+2.160	<.001	<.001	3	9
BONE	AMOTL2 →	+2.532	+1.613	<.001	.003	1	10
SOFT_TISSUE	AP1S3 →	+1.651	+1.479	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,731 associations by consensus.

WWC1 vs TUFT1 — BONE

Explore this scatter interactively →