WTIP

Across TCGA cell cohorts, WTIP RNA expression is significantly associated with the go_rna of many other GO terms, with 5,404 significant associations in total. BONE shows the largest number of these associations.

The most reproducible WTIP-associated GO terms across cancer lineages are Cell division, Regulation of protein K48-linked ubiquitination, and Regulation of early endosome to late endosome transport. Each is linked with WTIP in more than 13 cancer types. Because this analysis shows association rather than direction, both WTIP-to-partner and partner-to-WTIP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cell division grouped by WTIP-low versus WTIP-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (WTIP→partner) and Y-score (partner→WTIP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Cell division →	+0.079	+2.201	.002	<.001	3	14
LUNG_NSCLC_LUAD	Regulation of protein K48-linked ubiquitination →	+0.149	+1.754	<.001	<.001	3	13
OESOPHAGUS	Regulation of early endosome to late endosome transport →	+0.120	+1.816	.001	<.001	3	12
LUNG_NSCLC_LUSC	Regulation of hippo signaling →	+0.104	+2.157	.003	.009	2	13
STOMACH	Negative regulation of smoothened signaling pathway →	+0.065	+1.880	.002	.001	3	12
BONE	Regulation of cell-substrate junction organization →	+0.133	+1.961	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,404 associations by consensus.

Cell division by WTIP expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →