WTAP

Across TCGA patient cohorts, WTAP protein abundance is significantly associated with the RNA expression of many other genes, with 15,720 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible WTAP-associated genes across cancer lineages are NCAPD2, TTK, and CENPF. Each is linked with WTAP in more than 6 cancer types. Because this analysis shows association rather than direction, both WTAP-to-partner and partner-to-WTAP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, WTAP versus NCAPD2 in HNSC, with a Pearson correlation of 0.46.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WTAP→partner) and Y-score (partner→WTAP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	NCAPD2 →	+0.960	+0.193	<.001	<.001	3	7
LSCC	TTK →	+1.110	+0.214	<.001	<.001	3	7
UCEC	CENPF →	+1.077	+0.173	<.001	<.001	3	7
LUAD	KIF14 →	+0.992	+0.150	<.001	<.001	3	7
LSCC	HELLS →	+0.892	+0.185	<.001	<.001	3	7
UCEC	LTV1 →	+0.768	+0.222	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,720 associations by consensus.

WTAP vs NCAPD2 — HNSC

Explore this scatter interactively →