Across TCGA patient cohorts, WT1-AS RNA expression is significantly associated with the protein abundance of many other proteins, with 11,408 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible WT1-AS-associated proteins across cancer lineages are MRC2, C8B, and C8G. Each is linked with WT1-AS in more than 5 cancer types. Because this analysis shows association rather than direction, both WT1-AS-to-partner and partner-to-WT1-AS results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (WT1-AS→partner) and Y-score (partner→WT1-AS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	MRC2 →	+0.757	+0.358	<.001	<.001	3	6
COAD	C8B →	+0.480	+0.196	.001	<.001	3	5
HNSC	C8G →	+0.384	+0.197	<.001	.002	3	5
LSCC	PLIN3_S130 →	+0.694	+0.281	<.001	.004	3	5
UCEC	PTGIS →	+1.096	+1.250	<.001	<.001	3	5
COAD	SERPINF1 →	+0.750	+0.132	<.001	.005	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,408 associations by consensus.

Exploration

WT1-AS survival (RNA) · tumor vs normal (RNA) · all WT1-AS data types