WSCD2

Across TCGA patient cohorts, WSCD2 mutation is significantly associated with the RNA expression of many other genes, with 5,308 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible WSCD2-associated genes across cancer lineages are FOXM1, PKN3, and STIP1. Each is linked with WSCD2 in more than 4 cancer types. Because this analysis shows association rather than direction, both WSCD2-to-partner and partner-to-WSCD2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FOXM1 grouped by WSCD2-low versus WSCD2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WSCD2→partner) and Y-score (partner→WSCD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FOXM1 →	+0.665	+3.042	.001	<.001	3	5
UCEC	PKN3 →	+0.600	+1.868	<.001	<.001	3	5
UCEC	STIP1 →	+0.398	+1.483	<.001	.007	3	5
LUAD	STRN4 →	+0.437	+2.854	.004	.001	3	4
LUAD	OGFOD2 →	+0.259	+2.878	.006	.001	3	4
SKCM	DDX55 →	+0.535	+2.006	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,308 associations by consensus.

FOXM1 by WSCD2 expression — UCEC

Explore this box plot interactively →