WSB2

Across TCGA cell cohorts, WSB2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,832 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible WSB2-associated GO terms across cancer lineages are Positive regulation of postsynaptic membrane organization, Positive regulation of AMPA glutamate receptor clustering, and Positive regulation of SREBP signaling pathway. Each is linked with WSB2 in more than 10 cancer types. Because this analysis shows association rather than direction, both WSB2-to-partner and partner-to-WSB2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of postsynaptic membrane organization grouped by WSB2-low versus WSB2-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (WSB2→partner) and Y-score (partner→WSB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Positive regulation of postsynaptic membrane organization →	+0.120	+0.509	.003	.001	3	11
SKIN	Positive regulation of AMPA glutamate receptor clustering →	+0.120	+0.509	.003	.001	3	11
LUNG_SCLC	Positive regulation of SREBP signaling pathway →	+0.110	+0.776	.004	.009	3	9
STOMACH	Phosphatidylinositol dephosphorylation →	+0.051	+1.066	.005	<.001	2	10
LUNG_NSCLC_LUSC	Macroautophagy →	+0.060	+0.668	<.001	<.001	3	8
SKIN	1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate metabolic process →	+0.101	+0.691	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,832 associations by consensus.

Positive regulation of postsynaptic membrane organization by WSB2 expression — SKIN

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