WSB2

Across TCGA cell cohorts, WSB2 mutation is significantly associated with the mutation status of many other genes, with 1,562 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible WSB2-associated genes across cancer lineages are BANP, ANGPT4, and STARD7. Each is linked with WSB2 in more than 2 cancer types. Because this analysis shows association rather than direction, both WSB2-to-partner and partner-to-WSB2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BANP grouped by WSB2-low versus WSB2-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WSB2→partner) and Y-score (partner→WSB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	BANP →	+4.430	+3.823	.001	.001	1	3
BLOOD_Leukemia	ANGPT4 →	+3.430	+3.313	.005	.005	1	3
LARGE_INTESTINE	STARD7 →	+5.523	+5.523	.003	.003	1	2
BLOOD_Leukemia	ZSCAN21 →	+4.430	+3.823	.001	.001	1	2
BLOOD_Leukemia	MEI1 →	+3.845	+3.548	.003	.003	1	2
BLOOD_Leukemia	EEF2 →	+3.582	+4.084	<.001	<.001	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,562 associations by consensus.

BANP by WSB2 expression — BLOOD_Leukemia

Explore this box plot interactively →