WRBP1

Across TCGA patient cohorts, WRBP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,870 significant associations in total. STAD shows the largest number of these associations.

The most reproducible WRBP1-associated GO terms across cancer lineages are Transcription initiation at RNA polymerase II promoter, Protein localization to nuclear body, and Protein-containing complex disassembly. Each is linked with WRBP1 in more than 12 cancer types. Because this analysis shows association rather than direction, both WRBP1-to-partner and partner-to-WRBP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Transcription initiation at RNA polymerase II promoter grouped by WRBP1-low versus WRBP1-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (WRBP1→partner) and Y-score (partner→WRBP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Transcription initiation at RNA polymerase II promoter →	+0.076	+0.121	<.001	<.001	3	13
ESCA	Protein localization to nuclear body →	+0.078	+0.097	<.001	<.001	3	12
ESCA	Protein-containing complex disassembly →	+0.075	+0.065	<.001	<.001	3	11
ESCA	snRNA metabolic process →	+0.085	+0.067	<.001	<.001	3	11
ESCA	snRNA transcription →	+0.084	+0.072	<.001	<.001	3	11
ESCA	Regulation of mRNA catabolic process →	+0.069	+0.060	<.001	.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,870 associations by consensus.

Transcription initiation at RNA polymerase II promoter by WRBP1 expression — ESCA

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