WRBP1

Across TCGA pan-cancer cohorts, WRBP1 RNA is linked to patient survival in 16 of 34 cancer types, making it the most broadly survival-associated WRBP1 data layer.

The strongest signal is observed in cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC), where higher WRBP1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated WRBP1 expression acts as an unfavorable survival marker, although some lineages such as SKCM and UCS show a favorable association.

CESC, HNSC, and SKCM are the cancer types where WRBP1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CESC	OS	Tertile	III,IV	0.187	0.689	<.001	108	view →
HNSC	OS	Tertile	All	0.456	0.738	<.001	51	view →
SKCM	OS	Tertile	All	0.939	0.852	.001	45	view →
UCS	DFS	Quartile	II,III,IV	0.695	0.167	.002	38	view →
UCEC	OS	Tertile	IV	0.278	0.791	<.001	36	view →
BRCA	DFS	Tertile	IV	0.285	0.663	.011	15	view →
KIRC	OS	Tertile	All	0.697	0.590	.026	14	view →
CHOL	OS	Tertile	All	1.000	0.335	.024	9	view →
THCA	DFS	Tertile	IV	0.597	0.902	.045	9	view →
ACC	DFS	Median	IV	0.453	0.108	.019	9	view →
STAD	OS	Tertile	III,IV	0.727	0.340	.034	6	view →
LGG	OS	Tertile	All	0.334	0.534	.009	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 16 lineages.

WRBP1–CESC (OS)

Open the CESC breakdown →