WNT9A

Across TCGA patient cohorts, WNT9A mutation is significantly associated with the RNA expression of many other genes, with 126 significant associations in total. COAD shows the largest number of these associations.

The most reproducible WNT9A-associated genes across cancer lineages are MIR6882, DNAJC19P1, and RNA5SP319. Each is linked with WNT9A in more than 1 cancer types. Because this analysis shows association rather than direction, both WNT9A-to-partner and partner-to-WNT9A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR6882 grouped by WNT9A-low versus WNT9A-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WNT9A→partner) and Y-score (partner→WNT9A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	MIR6882 →	+0.386	+3.943	<.001	.002	3	2
HNSC	DNAJC19P1 →	+0.154	+4.912	<.001	.005	3	2
COAD	RNA5SP319 →	+0.430	+4.271	.008	.003	3	2
STAD	RNU7-73P →	+0.324	+4.678	.001	.007	3	2
LUAD	ZDHHC20P2 →	+0.057	+4.612	<.001	.006	3	2
UCEC	RNA5SP414 →	+0.745	+2.670	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 126 associations by consensus.

MIR6882 by WNT9A expression — SKCM

Explore this box plot interactively →