WNT9A

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, WNT9A mutation is significantly associated with the total protein of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible WNT9A-associated genes across cancer lineages are ARID1A and MSH2. Each is linked with WNT9A in more than 1 cancer types. Because this analysis shows association rather than direction, both WNT9A-to-partner and partner-to-WNT9A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ARID1A grouped by WNT9A-low versus WNT9A-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WNT9A→partner) and Y-score (partner→WNT9A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECARID1A →-0.291-2.992.005.03631
UCECMSH2 →-0.262-3.000.049.03711
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

ARID1A by WNT9A expression — UCEC

Box plot of ARID1A in WNT9A-low vs WNT9A-high samples in UCEC.

Explore this box plot interactively →

Exploration