WNT9A

Across TCGA cell cohorts, WNT9A RNA expression is significantly associated with the go_rna of many other GO terms, with 3,653 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible WNT9A-associated GO terms across cancer lineages are Release of cytochrome c from mitochondria, Regulation of nucleocytoplasmic transport, and Maintenance of cell polarity. Each is linked with WNT9A in more than 10 cancer types. Because this analysis shows association rather than direction, both WNT9A-to-partner and partner-to-WNT9A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Release of cytochrome c from mitochondria grouped by WNT9A-low versus WNT9A-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (WNT9A→partner) and Y-score (partner→WNT9A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Release of cytochrome c from mitochondria →	+0.123	+1.446	.002	.002	2	11
SKIN	Regulation of nucleocytoplasmic transport →	+0.057	+1.002	<.001	.002	3	9
URINARY_TRACT	Maintenance of cell polarity →	+0.134	+1.346	.003	.004	3	8
CNS	Septin ring organization →	+0.089	+1.137	<.001	<.001	3	8
PANCREAS	Spliceosomal tri-snRNP complex assembly →	+0.092	+1.599	<.001	<.001	3	8
LUNG_NSCLC_LUAD	Cornea development in camera-type eye →	+1.324	+2.169	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,653 associations by consensus.

Release of cytochrome c from mitochondria by WNT9A expression — BONE

Explore this box plot interactively →