WNT8A

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, WNT8A mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible WNT8A-associated genes across cancer lineages are MAGEB4. Each is linked with WNT8A in more than 1 cancer types. Because this analysis shows association rather than direction, both WNT8A-to-partner and partner-to-WNT8A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MAGEB4 grouped by WNT8A-low versus WNT8A-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WNT8A→partner) and Y-score (partner→WNT8A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINEMAGEB4 →+0.012+5.415.009.00431
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

MAGEB4 by WNT8A expression — LARGE_INTESTINE

Box plot of MAGEB4 in WNT8A-low vs WNT8A-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration