Across TCGA patient cohorts, WNT7B RNA expression is significantly associated with the protein abundance of many other proteins, with 10,689 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible WNT7B-associated proteins across cancer lineages are KRT19, SPECC1L, and PLEC. Each is linked with WNT7B in more than 4 cancer types. Because this analysis shows association rather than direction, both WNT7B-to-partner and partner-to-WNT7B results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (WNT7B→partner) and Y-score (partner→WNT7B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	KRT19 →	+0.929	+0.824	<.001	.002	3	5
OV	SPECC1L →	+0.314	+0.867	<.001	<.001	3	5
BRCA	PLEC →	+0.425	+1.381	<.001	<.001	3	5
LSCC	GPC1 →	+0.800	+1.029	<.001	<.001	3	4
PDAC	ZNF185 →	+0.645	+1.028	<.001	<.001	3	4
PDAC	PLAU →	+0.717	+0.865	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,689 associations by consensus.

Exploration

WNT7B survival (RNA) · tumor vs normal (RNA) · all WNT7B data types