Across TCGA patient cohorts, WNT7B protein abundance is significantly associated with the RNA expression of many other genes, with 3,218 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible WNT7B-associated genes across cancer lineages are PIK3C2G, RBFOX2, and GRAP2. Each is linked with WNT7B in more than 1 cancer types. Because this analysis shows association rather than direction, both WNT7B-to-partner and partner-to-WNT7B results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WNT7B→partner) and Y-score (partner→WNT7B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PIK3C2G →	+1.160	+1.041	.006	.001	3	2
LSCC	RBFOX2 →	+0.573	+1.022	<.001	<.001	3	2
HNSC	GRAP2 →	-1.394	-1.245	<.001	<.001	3	2
HNSC	SLA2 →	-1.340	-0.815	.001	.004	3	2
HNSC	NFATC2 →	-1.348	-0.989	.002	.002	3	2
HNSC	LPIN2 →	-0.668	-0.843	.005	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,218 associations by consensus.

Exploration

WNT7B survival (RNA) · tumor vs normal (RNA) · all WNT7B data types