Across TCGA cell cohorts, WNT7B mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible WNT7B-associated genes across cancer lineages are OR14A16, TPD52L3, and CTXN3. Each is linked with WNT7B in more than 1 cancer types. Because this analysis shows association rather than direction, both WNT7B-to-partner and partner-to-WNT7B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WNT7B→partner) and Y-score (partner→WNT7B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	OR14A16 →	+0.017	+4.643	<.001	.005	3	1
BLOOD_Leukemia	TPD52L3 →	+0.012	+5.539	<.001	.003	3	1
BLOOD_Leukemia	CTXN3 →	+0.012	+5.201	<.001	.006	3	1
BLOOD_Leukemia	CFHR2 →	+0.151	+5.539	.002	.003	3	1
LARGE_INTESTINE	OR10W1 →	+0.012	+4.977	.002	.007	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Exploration

WNT7B survival (RNA) · tumor vs normal (RNA) · all WNT7B data types