WNT7A

Across TCGA patient cohorts, WNT7A protein abundance is significantly associated with the protein abundance of many other proteins, with 2,557 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible WNT7A-associated proteins across cancer lineages are IST1, MMP14, and NNMT. Each is linked with WNT7A in more than 1 cancer types. Because this analysis shows association rather than direction, both WNT7A-to-partner and partner-to-WNT7A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, WNT7A versus IST1 in UCEC, with a Pearson correlation of -0.68.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (WNT7A→partner) and Y-score (partner→WNT7A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	IST1 →	-0.254	-1.104	<.001	<.001	3	2
HNSC	MMP14 →	+0.527	+1.156	.001	<.001	3	2
OV	NNMT →	+0.910	+0.958	.002	<.001	3	2
UCEC	PDCD4 →	-0.448	-1.051	<.001	.001	3	2
UCEC	LRRC41_S357 →	-0.813	-1.564	.002	.002	3	2
HNSC	NASP_S421 →	+1.669	+1.142	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,557 associations by consensus.

WNT7A vs IST1 — UCEC

Explore this scatter interactively →