WNT7A

Across TCGA cell cohorts, WNT7A RNA expression is significantly associated with the go_rna of many other GO terms, with 2,100 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible WNT7A-associated GO terms across cancer lineages are Cell-substrate junction assembly, Regulation of ventricular cardiac muscle cell action potential, and Small GTPase-mediated signal transduction. Each is linked with WNT7A in more than 8 cancer types. Because this analysis shows association rather than direction, both WNT7A-to-partner and partner-to-WNT7A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cell-substrate junction assembly grouped by WNT7A-low versus WNT7A-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (WNT7A→partner) and Y-score (partner→WNT7A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Cell-substrate junction assembly →	+0.164	+2.233	<.001	<.001	3	9
OVARY	Regulation of ventricular cardiac muscle cell action potential →	+0.183	+2.138	.002	.004	3	8
URINARY_TRACT	Small GTPase-mediated signal transduction →	+0.051	+1.869	<.001	<.001	3	8
URINARY_TRACT	Cell-substrate junction organization →	+0.152	+2.233	<.001	<.001	3	8
OVARY	Positive regulation of excitatory synapse assembly →	+1.671	+4.093	<.001	<.001	3	8
BREAST	Hemidesmosome assembly →	+0.278	+1.190	<.001	.005	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,100 associations by consensus.

Cell-substrate junction assembly by WNT7A expression — URINARY_TRACT

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