WNT3A

Across TCGA patient cohorts, WNT3A protein abundance is significantly associated with the RNA expression of many other genes, with 39 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible WNT3A-associated genes across cancer lineages are RBFOX2, PRPH2, and NECAB1. Each is linked with WNT3A in more than 1 cancer types. Because this analysis shows association rather than direction, both WNT3A-to-partner and partner-to-WNT3A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, WNT3A versus RBFOX2 in LSCC, with a Pearson correlation of 0.51.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WNT3A→partner) and Y-score (partner→WNT3A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	RBFOX2 →	+0.839	+0.160	.004	.001	1	1
LSCC	PRPH2 →	+1.159	+0.160	.008	.001	1	1
LSCC	NECAB1 →	+0.429	+0.160	.002	.001	1	1
LSCC	LARGE1 →	+0.825	+0.160	.003	.001	1	1
LSCC	FAM189A2 →	+0.939	+0.160	.003	.001	1	1
LSCC	CHST4 →	+1.924	+0.160	.003	.001	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 39 associations by consensus.

WNT3A vs RBFOX2 — LSCC

Explore this scatter interactively →