WNT3A

Across TCGA cell cohorts, WNT3A RNA expression is significantly associated with the go_rna of many other GO terms, with 1,018 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible WNT3A-associated GO terms across cancer lineages are Cell proliferation in midbrain, Regulation of syncytium formation by plasma membrane fusion, and Respiratory electron transport chain. Each is linked with WNT3A in more than 11 cancer types. Because this analysis shows association rather than direction, both WNT3A-to-partner and partner-to-WNT3A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cell proliferation in midbrain grouped by WNT3A-low versus WNT3A-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (WNT3A→partner) and Y-score (partner→WNT3A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Cell proliferation in midbrain →	+0.786	+1.580	<.001	<.001	3	12
OESOPHAGUS	Regulation of syncytium formation by plasma membrane fusion →	+0.102	+0.920	<.001	<.001	3	8
OESOPHAGUS	Respiratory electron transport chain →	+0.097	+0.780	.005	.002	3	8
OESOPHAGUS	ATP metabolic process →	+0.106	+0.751	<.001	.005	3	8
OESOPHAGUS	RNA polymerase II preinitiation complex assembly →	+0.069	+0.848	.004	.001	3	8
OESOPHAGUS	ATP synthesis coupled electron transport →	+0.094	+0.735	.001	.007	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,018 associations by consensus.

Cell proliferation in midbrain by WNT3A expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →