WNT16

Across TCGA cell cohorts, WNT16 RNA expression is significantly associated with the go_rna of many other GO terms, with 990 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible WNT16-associated GO terms across cancer lineages are Regulation of intracellular transport, Positive regulation of intracellular transport, and Negative regulation of endothelial cell proliferation. Each is linked with WNT16 in more than 6 cancer types. Because this analysis shows association rather than direction, both WNT16-to-partner and partner-to-WNT16 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of intracellular transport grouped by WNT16-low versus WNT16-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (WNT16→partner) and Y-score (partner→WNT16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Regulation of intracellular transport →	+0.061	+0.501	.001	.007	3	7
CNS	Positive regulation of intracellular transport →	+0.044	+0.204	<.001	.004	2	7
CNS	Negative regulation of endothelial cell proliferation →	+0.109	+0.337	<.001	<.001	3	5
LUNG_NSCLC_LUSC	Oxidative stress-induced premature senescence →	-1.068	-0.529	.002	.009	3	5
SKIN	Regulation of stem cell population maintenance →	+0.039	+0.176	.009	.001	3	5
LUNG_NSCLC_LUSC	Monocyte activation →	+0.098	+0.560	.002	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 990 associations by consensus.

Regulation of intracellular transport by WNT16 expression — STOMACH

Explore this box plot interactively →