WNK4

Across TCGA patient cohorts, WNK4 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,148 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible WNK4-associated proteins across cancer lineages are WNK4_S1217, VEZF1, and RRBP1. Each is linked with WNK4 in more than 4 cancer types. Because this analysis shows association rather than direction, both WNK4-to-partner and partner-to-WNK4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, WNK4 versus WNK4_S1217 in BRCA, with a Pearson correlation of 0.83.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (WNK4→partner) and Y-score (partner→WNK4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	WNK4_S1217 →	+2.749	+2.327	<.001	<.001	3	5
BRCA	VEZF1 →	+0.524	+1.732	<.001	<.001	3	4
LSCC	RRBP1 →	-0.318	-0.380	<.001	<.001	3	4
BRCA	ISG20 →	-0.521	-1.370	.001	<.001	3	4
LUAD	C1orf226_S198 →	+1.176	+0.452	<.001	<.001	3	4
LSCC	PARVG →	-0.426	-0.422	.001	.008	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,148 associations by consensus.

WNK4 vs WNK4_S1217 — BRCA

Explore this scatter interactively →