WNK4

Across TCGA patient cohorts, WNK4 protein abundance is significantly associated with the RNA expression of many other genes, with 8,660 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible WNK4-associated genes across cancer lineages are TP53I3, IGHV1OR15-9, and DYNLL1P7. Each is linked with WNK4 in more than 1 cancer types. Because this analysis shows association rather than direction, both WNK4-to-partner and partner-to-WNK4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, WNK4 versus TP53I3 in COAD, with a Pearson correlation of -0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WNK4→partner) and Y-score (partner→WNK4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	TP53I3 →	-0.622	-0.685	.005	.002	3	2
UCEC	IGHV1OR15-9 →	+0.982	+2.528	.001	<.001	3	2
BRCA	DYNLL1P7 →	-0.433	-0.490	.007	.005	3	2
UCEC	LINC01697 →	-1.072	-1.447	.002	.005	3	2
COAD	LINC02323 →	-0.601	-0.506	<.001	.008	3	2
BRCA	ALB →	+1.125	+0.580	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,660 associations by consensus.

WNK4 vs TP53I3 — COAD

Explore this scatter interactively →