WIZP1

Across TCGA pan-cancer cohorts, WIZP1 RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated WIZP1 data layer.

The strongest signal is observed in lymphoid neoplasm diffuse large b-cell lymphoma (DLBC), where higher WIZP1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated WIZP1 expression acts as an unfavorable survival marker, although some lineages such as KIRC and ESCA show a favorable association.

DLBC, THCA, and SKCM are the cancer types where WIZP1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
DLBC	OS	Tertile	All	0.659	0.958	<.001	153	view →
THCA	DFS	Quartile	II,III,IV	0.508	0.791	<.001	73	view →
SKCM	DFS	Quartile	All	0.582	0.770	<.001	35	view →
KIRC	DFS	Tertile	III,IV	0.909	0.664	.006	30	view →
STAD	DFS	Quartile	IV	0.157	0.593	.008	28	view →
ESCA	OS	Tertile	III,IV	0.810	0.436	.005	25	view →
CESC	DFS	Tertile	II,III,IV	0.874	0.415	.010	24	view →
GBM	DFS	Median	All	0.394	0.185	.001	24	view →
UCS	DFS	Tertile	IV	0.996	0.570	.039	18	view →
COAD	OS	Tertile	All	0.648	0.830	.013	12	view →
MESO	OS	Tertile	IV	0.437	0.619	.048	9	view →
READ	OS	Tertile	IV	0.077	1.000	.014	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

WIZP1–DLBC (OS)

Open the DLBC breakdown →