Across TCGA pan-cancer cohorts, WIZP1 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of WIZP1’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where WIZP1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types WIZP1 is over-expressed in tumor.
KIRP, HNSC, and LIHC are the cancer types where WIZP1 tumor–normal differential expression is most reproducible.