WIZ

Across TCGA patient cohorts, WIZ RNA expression is significantly associated with the protein abundance of many other proteins, with 13,261 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible WIZ-associated proteins across cancer lineages are TRIM28, SF3B3, and FMNL1_S184. Each is linked with WIZ in more than 4 cancer types. Because this analysis shows association rather than direction, both WIZ-to-partner and partner-to-WIZ results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, WIZ versus TRIM28 in GBM, with a Pearson correlation of 0.44.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (WIZ→partner) and Y-score (partner→WIZ) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	TRIM28 →	+0.466	+0.497	<.001	<.001	3	5
GBM	SF3B3 →	+0.268	+0.392	<.001	.001	3	5
LSCC	FMNL1_S184 →	-0.980	-0.658	<.001	<.001	3	5
OV	DENND2D →	-0.599	-1.229	.002	.002	3	5
GBM	PNN →	+0.376	+0.482	<.001	<.001	3	4
GBM	RBBP4 →	+0.411	+0.470	.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,261 associations by consensus.

WIZ vs TRIM28 — GBM

Explore this scatter interactively →