WHAMMP3

Across TCGA patient cohorts, WHAMMP3 mutation is significantly associated with the total protein of many other genes, with 20 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible WHAMMP3-associated genes across cancer lineages are INPP4B, Myosin-IIa_pS1943, and Myosin-IIa. Each is linked with WHAMMP3 in more than 1 cancer types. Because this analysis shows association rather than direction, both WHAMMP3-to-partner and partner-to-WHAMMP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, INPP4B grouped by WHAMMP3-low versus WHAMMP3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WHAMMP3→partner) and Y-score (partner→WHAMMP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	INPP4B →	-0.428	-3.169	.011	.019	3	1
UCEC	Myosin-IIa_pS1943 →	+0.291	+3.335	.007	.005	3	1
UCEC	Myosin-IIa →	+0.242	+2.177	.012	.035	3	1
UCEC	Tuberin →	+0.441	+3.321	.001	.010	3	1
UCEC	VHL →	-1.147	-3.169	.001	.019	3	1
UCEC	ASNS →	+0.496	+2.999	.008	.035	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 20 associations by consensus.

INPP4B by WHAMMP3 expression — UCEC

Explore this box plot interactively →