WHAMMP3

Across TCGA pan-cancer cohorts, WHAMMP3 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated WHAMMP3 data layer compared with 2 for mutation status.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher WHAMMP3 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated WHAMMP3 expression acts as an unfavorable survival marker, although some lineages such as KIRP and PAAD show a favorable association.

KIRP, LAML, and DLBC are the cancer types where WHAMMP3 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	DFS	Median	All	0.954	0.568	<.001	40	view →
LAML	DFS	Median	All	0.473	0.664	.002	38	view →
DLBC	DFS	Median	IV	0.128	1.000	.017	20	view →
PAAD	DFS	Quartile	All	0.654	0.400	.009	19	view →
CHOL	OS	Quartile	II,III,IV	0.961	0.248	.014	18	view →
STAD	OS	Median	III,IV	0.435	0.600	.012	15	view →
LUAD	OS	Tertile	All	0.850	0.759	.007	13	view →
SKCM	DFS	Median	All	0.669	0.568	.005	12	view →
SARC	OS	Quartile	All	0.867	0.731	.015	12	view →
UVM	DFS	Median	III,IV	0.302	0.714	.035	6	view →
MESO	OS	Tertile	All	0.597	0.199	.019	6	view →
LGG	DFS	Quartile	All	0.750	0.903	.007	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

WHAMMP3–KIRP (DFS)

Open the KIRP breakdown →