WFIKKN2

Across TCGA patient cohorts, WFIKKN2 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,111 significant associations in total. STAD shows the largest number of these associations.

The most reproducible WFIKKN2-associated GO terms across cancer lineages are Negative regulation of growth, Protein stabilization, and Regulation of canonical Wnt signaling pathway. Each is linked with WFIKKN2 in more than 20 cancer types. Because this analysis shows association rather than direction, both WFIKKN2-to-partner and partner-to-WFIKKN2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of growth grouped by WFIKKN2-low versus WFIKKN2-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (WFIKKN2→partner) and Y-score (partner→WFIKKN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Negative regulation of growth →	+0.057	+0.183	<.001	<.001	3	21
STAD	Protein stabilization →	+0.062	+0.163	<.001	<.001	3	20
STAD	Regulation of canonical Wnt signaling pathway →	+0.060	+0.169	<.001	<.001	3	19
STAD	Negative regulation of cell growth →	+0.062	+0.168	<.001	<.001	3	19
TGCT	Kidney epithelium development →	+0.061	+1.162	<.001	<.001	3	19
STAD	Connective tissue development →	+0.059	+0.161	<.001	<.001	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,111 associations by consensus.

Negative regulation of growth by WFIKKN2 expression — STAD

Explore this box plot interactively →