WFIKKN2

Across TCGA cell cohorts, WFIKKN2 RNA expression is significantly associated with the go_rna of many other GO terms, with 762 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible WFIKKN2-associated GO terms across cancer lineages are Co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway, Negative regulation of myoblast fusion, and Negative regulation of syncytium formation by plasma membrane fusion. Each is linked with WFIKKN2 in more than 5 cancer types. Because this analysis shows association rather than direction, both WFIKKN2-to-partner and partner-to-WFIKKN2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway grouped by WFIKKN2-low versus WFIKKN2-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (WFIKKN2→partner) and Y-score (partner→WFIKKN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway →	+0.069	+0.011	<.001	<.001	3	6
LARGE_INTESTINE	Negative regulation of myoblast fusion →	+0.072	+0.035	.005	.005	3	6
LARGE_INTESTINE	Negative regulation of syncytium formation by plasma membrane fusion →	+0.067	+0.034	.007	.007	3	6
SOFT_TISSUE	Regulation of RNA splicing →	+0.075	+0.106	<.001	.004	3	6
LUNG_NSCLC_LUAD	Regulation of syncytium formation by plasma membrane fusion →	+0.058	+0.015	<.001	<.001	3	6
BLOOD_Lymphoma	RNA catabolic process →	+0.040	+0.015	<.001	.006	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 762 associations by consensus.

Co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway by WFIKKN2 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →