WFIKKN1

Across TCGA patient cohorts, WFIKKN1 protein abundance is significantly associated with the RNA expression of many other genes, with 338 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible WFIKKN1-associated genes across cancer lineages are LAMA1, RHBDL1, and EARS2. Each is linked with WFIKKN1 in more than 1 cancer types. Because this analysis shows association rather than direction, both WFIKKN1-to-partner and partner-to-WFIKKN1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, WFIKKN1 versus LAMA1 in CCRCC, with a Pearson correlation of 0.43.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WFIKKN1→partner) and Y-score (partner→WFIKKN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	LAMA1 →	+1.170	+0.566	<.001	<.001	3	1
CCRCC	RHBDL1 →	+0.656	+0.554	.009	.007	3	1
CCRCC	EARS2 →	+0.455	+0.684	<.001	.001	3	1
CCRCC	DNAJA3 →	+0.255	+0.486	<.001	.001	3	1
CCRCC	GCDH →	+0.280	+0.501	.002	.005	3	1
CCRCC	QKI →	-0.298	-0.499	.003	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 338 associations by consensus.

WFIKKN1 vs LAMA1 — CCRCC

Explore this scatter interactively →