WFIKKN1

Across TCGA cell cohorts, WFIKKN1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,074 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible WFIKKN1-associated GO terms across cancer lineages are Pre-mRNA catabolic process, Cilium movement involved in cell motility, and Sperm motility. Each is linked with WFIKKN1 in more than 13 cancer types. Because this analysis shows association rather than direction, both WFIKKN1-to-partner and partner-to-WFIKKN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Pre-mRNA catabolic process grouped by WFIKKN1-low versus WFIKKN1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (WFIKKN1→partner) and Y-score (partner→WFIKKN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Pre-mRNA catabolic process →	+0.257	+0.248	<.001	.009	3	14
UPPER_AERODIGESTIVE_TRACT	Cilium movement involved in cell motility →	-0.117	-0.287	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Sperm motility →	-0.112	-0.259	.003	.004	3	11
PANCREAS	Calcium-independent cell-matrix adhesion →	+0.162	+0.465	.001	.006	2	12
UPPER_AERODIGESTIVE_TRACT	Regulation of myoblast fusion →	+0.088	+0.218	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Regulation of syncytium formation by plasma membrane fusion →	+0.079	+0.222	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,074 associations by consensus.

Pre-mRNA catabolic process by WFIKKN1 expression — BONE

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