WFDC6

Across TCGA patient cohorts, WFDC6 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,069 significant associations in total. STAD shows the largest number of these associations.

The most reproducible WFDC6-associated GO terms across cancer lineages are Organelle disassembly, Protein localization to endoplasmic reticulum, and Membrane lipid metabolic process. Each is linked with WFDC6 in more than 14 cancer types. Because this analysis shows association rather than direction, both WFDC6-to-partner and partner-to-WFDC6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Organelle disassembly grouped by WFDC6-low versus WFDC6-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (WFDC6→partner) and Y-score (partner→WFDC6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Organelle disassembly →	+0.084	+0.167	<.001	<.001	3	15
STAD	Protein localization to endoplasmic reticulum →	+0.096	+0.187	<.001	<.001	3	14
STAD	Membrane lipid metabolic process →	+0.062	+0.187	<.001	<.001	3	14
STAD	Regulation of cell projection assembly →	+0.066	+0.178	<.001	<.001	3	14
STAD	Entrainment of circadian clock →	+0.062	+0.139	<.001	<.001	3	14
STAD	Vesicle-mediated transport to the plasma membrane →	+0.078	+0.177	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,069 associations by consensus.

Organelle disassembly by WFDC6 expression — STAD

Explore this box plot interactively →