WFDC13

Across TCGA patient cohorts, WFDC13 mutation is significantly associated with the RNA expression of many other genes, with 17 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible WFDC13-associated genes across cancer lineages are RN7SL228P, LINC01661, and RN7SL831P. Each is linked with WFDC13 in more than 1 cancer types. Because this analysis shows association rather than direction, both WFDC13-to-partner and partner-to-WFDC13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL228P grouped by WFDC13-low versus WFDC13-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WFDC13→partner) and Y-score (partner→WFDC13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RN7SL228P →	+0.082	+4.993	<.001	.002	3	2
SKCM	LINC01661 →	+0.066	+4.097	<.001	.002	3	1
SKCM	RN7SL831P →	+0.204	+5.219	<.001	.002	3	1
SKCM	RN7SL189P →	+0.071	+4.199	<.001	.009	3	1
SKCM	TRPC7-AS2 →	+0.033	+4.797	<.001	.003	3	1
SKCM	LINC02304 →	+0.055	+4.624	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 17 associations by consensus.

RN7SL228P by WFDC13 expression — SKCM

Explore this box plot interactively →